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Title: Cyclofenil  
Author: World Heritage Encyclopedia
Language: English
Subject: Estrone sulfate, Testolactone, Antiestrogen, Estradiol enanthate, Estradiol cypionate
Collection: Acetate Esters, Selective Estrogen Receptor Modulators
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
[4-[(4-acetoxyphenyl)-cyclohexylidene-methyl]phenyl] acetate
Clinical data
Legal status
Routes Oral
CAS number
ATC code G03
Synonyms bis(p-acetoxyphenyl)cyclohexylidenemethane
Chemical data
Formula C23H24O4 
Mol. mass 364.434 g/mol

Cyclofenil (INN, trade names Ondogyne, Sexovid, and others) is a selective estrogen receptor modulator.

It was investigated as a possible treatment for scleroderma in the 1980s, but was found to be ineffective.[1] Later study of its efficacy in treating Raynaud's phenomenon in people with scleroderma also found no statistically significant benefit.[2]


  1. ^ Torres MA, Furst DE (February 1990). "Treatment of generalized systemic sclerosis". Rheum Dis Clin North Am 16 (1): 217–41.  
  2. ^ Pope J, Fenlon D, Thompson A, et al. (2000). Pope, Janet, ed. "Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis".  

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