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Deoxyadenosine is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety. Deoxyadenosine is the DNA nucleoside A, which pairs with deoxythymidine (T) in double-stranded DNA. In absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe combined immunodeficiency disease (ADA-SCID).[1]
Genetics, Biology, Metabolism, Molecular biology, Chemistry
Hydrogen, International Union of Pure and Applied Chemistry, World War I, Analytical chemistry, France
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Ribose, Nucleoside, Deoxyribose, Metabolism, Biology
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DNA replication, Bacteria, DNA repair, Methylase, Dna
DNA replication, Polymerase chain reaction, Purine, Ribose, Dna