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Estradiol enanthate

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Title: Estradiol enanthate  
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Subject: Hormonal contraception, Combined injectable contraceptive, Estrone sulfate, Antiestrogen, Clomifene
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Estradiol enanthate

Estradiol enanthate
Systematic (IUPAC) name
(17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl heptanoate
Clinical data
Legal status
  • Prescription only
Routes IM
CAS number
ATC code None
Synonyms 17β-Estradiol-17-heptanoate
Chemical data
Formula C25H36O3 
Mol. mass 384.552 g/mol

Estradiol enanthate (INN, USAN), or estradiol enantate, is a synthetic ester, specifically the 17-heptanoyl ester, of the natural estrogen, estradiol.[1][2] It is marketed under the brand names Anafertin, Deladroxate, Perlutan, and Topasel, which are combination formulations of estradiol enanthate and dihydroxyprogesterone acetophenide, as a once-monthly injectable hormonal contraceptive in Spain and Latin America,[3][4] and has been used as such since at least the mid-1960s.[5]

See also


  1. ^ A. D. Roberts (1991). Dictionary of Steroids: Chemical Data, Structures, and Bibliographies. CRC Press. p. 415.  
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 405.  
  3. ^ Zutshi (1 January 2005). Hormones in Obstetrics and Gynaecology. Jaypee Brothers Publishers. p. 138.  
  4. ^ Newton JR, D'arcangues C, Hall PE (1994). "A review of "once-a-month" combined injectable contraceptives". Journal of Obstetrics and Gynaecology. 4 Suppl 1: S1–34.  
  5. ^ Rizkallah TH, Taymor ML (January 1966). "Ovulation inhibition with a log-acting injectable. II. The cycling effects of varying progestagen-estrogen combinations". American Journal of Obstetrics and Gynecology 94 (2): 161–4.  

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