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Fancc

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Fancc

Fanconi anemia, complementation group C
Identifiers
FANCC Gene
RNA expression pattern
Fanconi anaemia group C protein
Identifiers
Symbol Fanconi_C
Pfam InterPro IPR000686

Fanconi anemia group C protein is a protein that in humans is encoded by the FANCC gene.[1][2]

The protein encoded by this gene delays the onset of apoptosis and promotes homologous recombination repair of damaged DNA. Mutations in this gene result in Fanconi anemia.[2]

Interactions

Fanconi anemia, complementation group C has been shown to interact with STAT1,[3][4][5] ZBTB32,[4][6] GSTP1,[4][7] Cdk1,[4][8] SPTAN1,[9][10] HSPA1A,[4][11] FANCF,[12][13] FANCA[10][13][14][15][16][17][18][19] and FANCE.[12][18][20][21][22]

References

Further reading

External links

  • GeneReviews/NCBI/NIH/UW entry on 9q22.3 Microdeletion
  • GeneReviews/NCBI/NIH/UW entry on Fanconi Anemia or Pancytopenia



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