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Title: Fadrozole  
Author: World Heritage Encyclopedia
Language: English
Subject: Cyproterone acetate, Cyanoketone, Cortodoxone, Metyrapone, 22R-Hydroxycholesterol
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
Legal status
  • Prescription only
Routes Oral
CAS number  YesY
ATC code None
ChemSpider  N
Chemical data
Formula C14H13N3 
Mol. mass 223.27 g/mol

Fadrozole (INN, marketed as Afema by Novartis) is an aromatase inhibitor[1] that has been introduced in Japan for the treatment of breast cancer.

It is selective.[2]


  1. ^ Raats JI, Falkson G, Falkson HC (January 1992). "A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced metastatic breast cancer". J. Clin. Oncol. 10 (1): 111–6.  
  2. ^ Browne LJ, Gude C, Rodriguez H, Steele RE, Bhatnager A (February 1991). "Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease". J. Med. Chem. 34 (2): 725–36.  

See also

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