World Library  
Flag as Inappropriate
Email this Article

Jules Bordet

Jules Bordet
Jules Bordet
Born Jules Jean Baptiste Vincent Bordet
(1870-06-13)13 June 1870
Died 6 April 1961(1961-04-06) (aged 90)
Resting place Ixelles Cemetery
Alma mater Free University of Brussels
Notable awards

Jules Jean Baptiste Vincent Bordet (13 June 1870 – 6 April 1961) was a Belgian immunologist and microbiologist. The bacterial genus Bordetella is named after him.


  • Education and early life 1
  • Career 2
  • Awards and honours 3
  • References 4
  • External links 5

Education and early life

Bordet was born at Soignies, Belgium. He graduated as Doctor of Medicine from the Free University of Brussels in 1892 and began his work at the Pasteur Institute in Paris in 1894, in the laboratory of Elie Metchnikoff, who had just discovered phagocytosis of bacteria by white blood cells, expression of the cellular immunity. In 1898 Bordet described hemolysis evoked by exposure of blood serum to foreign blood cells.


In 1900, he left Paris to found the Pasteur Institute in Brussels, and made his discovery that the bacteriolytic effect of acquired specific antibody is significantly enhanced in vivo by the presence of innate serum components which he termed alexine (but which are now known as complement). This mechanism became the basis for complement-fixation testing methods that enabled the development of serological tests for syphilis (specifically, the development of the Wassermann test by August von Wassermann). The same technique is used today in serologic testing for countless other diseases.

With Octave Gengou he isolated Bordetella pertussis in pure culture in 1906 and posited it as the cause of whooping cough. He became Professor of Bacteriology at the Université Libre de Bruxelles in 1907.

Jules Bordet's grave in Ixelles Cemetery

Awards and honours

In March 1916 he was elected a Fellow of the Royal Society[1] and in 1930 delivered their Croonian Lecture.[2] In this lecture Bordet also concluded that bacteriophages "the invisible virus of Felix d'Herelle",a self-taught microbiologist, did not exist and that it was bacteria themselves which produce the lytic principle. He was to be proven incorrect later with Bacteriophage therapy then recognised as an alternative/complementary therapy in the fight against bacterial infections, starting with the treatment of patients in Paris by Felix d'Herelle.[3] The Nobel Prize in Physiology or Medicine was awarded to him in 1919 for his discoveries relating to immunity.

Bordet died in 1961 and was interred in the Ixelles Cemetery in Brussels.


  1. ^ a b Oakley, C. L. (1962). "Jules Jean Baptiste Vincent Bordet 1870-1961".  
  2. ^ "Librart and Archive Catalogue". Royal society. Retrieved 18 December 2010. 
  3. ^ Hausler, Thomas (2007) Viruses Vs. Superbugs: A Solution to the Antibiotics Crisis? Palgrave Macmillan. ISBN 0230551939

External links

  • a longer Biography page at Jules Bordet Institute
  • The Nobel Prize in Physiology or Medicine 1919
  • Jules Bordet Institute
  • Jules Bordet at Find a Grave
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.