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Potassium inwardly-rectifying channel, subfamily J, member 2
PDB rendering based on 1u4f.
Available structures
PDB Ortholog search: RCSB
KCNJ2 Gene
RNA expression pattern

The Kir2.1

Clinical significance

A defect in this gene is associated with Andersen-Tawil syndrome.[4]

A mutation in the KCNJ2 gene has also been shown to cause short QT syndrome.[5]


Kir2.1 has been shown to interact with DLG4,[6] TRAK2[7] and Interleukin 16.[8]


Further reading

External links

  • GeneReviews/NCBI/NIH/UW entry on Andersen-Tawil syndrome
  • OMIM entries on Anderson-Tawil syndrome
  • Medical Subject Headings (MeSH)
  • Medical Subject Headings (MeSH)

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