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Knuckle pads

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Title: Knuckle pads  
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Subject: Dupuytren's contracture, ICD-10 Chapter XIII: Diseases of the musculoskeletal system and connective tissue
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Knuckle pads

Knuckle pads
Classification and external resources
ICD-10 9 OMIM DiseasesDB eMedicine article/1074379

Knuckle pads (also known as "Heloderma", meaning similar to the skin of the Gila monster lizard for which it is named) are circumscribed, keratotic, fibrous growths over the dorsa of the interphalangeal joints.[1] Knuckle pads are well-defined, round, plaque-like, fibrous thickening that may develop at any age, and grow to be 10 to 15mm in diameter in the course of a few weeks or months, then persist permanently.[2]:604 Knuckle pads are sometimes associated with Dupuytren's contracture and camptodactyly[2]:604, and histologically, the lesions are fibromas.[2]:605

See also



  • Guberman D, et al.: Kunckle pads-a forgotten skin condition: report of a case and review of the literature. Cutis 1996;57:241.
  • Ly Y, et al.: A novel mutation of keratin 9 in epidermolytic palmoplantar keratoderma combined with knuckle pads. Am J Med Genet 2003;120A:345.
  • Peterson CM, et al.: Knuckle pads: does knuckle cracking play an etiologic role? Pediatr Dermatol 2000;17:450.
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