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Title: Mkx  
Author: World Heritage Encyclopedia
Language: English
Subject: Iroquois homeobox factor, Homeobox, NeuroD, EMX homeogene, Nur (biology)
Publisher: World Heritage Encyclopedia


Mohawk homeobox
Symbols  ; C10orf48; IFRX; IRXL1
External IDs GeneCards:
Species Human Mouse
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX (mohawk homeobox) gene.[1]


MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.[1][2]


  1. ^ a b "Entrez Gene: mohawk homeobox". 
  2. ^ Anderson DM, Arredondo J, Hahn K, Valente G, Martin JF, Wilson-Rawls J, Rawls A (March 2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo". Dev. Dyn. 235 (3): 792–801.  

Further reading

  • Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1994). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.". Genomics 23 (1): 42–50.  
  • Weinmann A, Galle PR, Teufel A (2005). "In silico characterization of an Iroquois family-related homeodomain protein.". Int. J. Mol. Med. 16 (3): 443–8.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.  
  • Anderson DM, Arredondo J, Hahn K, et al. (2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo.". Dev. Dyn. 235 (3): 792–801.  
  • Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome.". Mol. Cell Proteomics 7 (3): 499–508.  

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