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Meesmann corneal dystrophy


Meesmann corneal dystrophy

Meesmann juvenile epithelial corneal dystrophy
Classification and external resources
Multiple opaque spots in the corneal epithelium
ICD-9 371.51
OMIM 122100
DiseasesDB 31962
MeSH D053559

Meesmann corneal dystrophy, also Stocker-Holt dystrophy, is a type of corneal dystrophy and a keratin disease.

It is named for German ophthalmologist Alois Meesmann (1888-1969).[1][2]

It is sometimes called "Meesmann-Wilke syndrome", after the joint contribution of Meesmann and Wilke.[1][3]


It has been associated with genes KRT3 and KRT12 located on chromosome 12 and 17 respectively.[4]

Clinical presentation

This slowly progressive disorder is characterized by small cysts in the epithelium of the cornea. Patients with Meesmann corneal dystrophy are intolerant of contact lenses, as these devices directly traumatize the corneal epithelium.

See also


  1. ^ a b synd/3139 at Who Named It?
  2. ^ A. Meesmann. Klinische und anatomische Untersuchungen über eine bisher unbekannte, dominant vererbte Dystrophia epithelialis corneae. Bericht der Deutschen ophthalmologischen Gesellschaft, Heidelberg, 1938, 52: 154-158.
  3. ^ A. Meesmann, F. Wilke. Klinische und anatomische Untersuchungen über eine bisher unbekannte, dominant vererbte Epithel Dystrophie der Horn haut. Klinische Monatsblätter für Augenheilkunde, Stuttgart, 1939, 103: 361-391.
  4. ^ Online 'Mendelian Inheritance in Man' (OMIM) 122100
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