World Library  
Flag as Inappropriate
Email this Article

Mesangium

Article Id: WHEBN0007593782
Reproduction Date:

Title: Mesangium  
Author: World Heritage Encyclopedia
Language: English
Subject: Extraglomerular mesangial cell, Intraglomerular mesangial cell, Medullary interstitium, Cortical lobule, Median umbilical ligament
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Mesangium

Renal corpuscle. The entire structure is the renal corpuscle. The blue structure (A) is the Bowman's capsule (2 and 3). The pink structure is the glomerulus with its capillaries. At the left, blood flows from the afferent arteriole (9), through the capillaries (10), and out the efferent arteriole (11). The mesangium is the pink structure inside the glomerulus between the capillaries (5a) and extending outside the glomerulus (5b).

In the glomerulus of the kidney, the mesangium is a structure associated with the capillaries. It is continuous with the smooth muscles of the arterioles. It is outside the capillary lumen, but surrounded by capillaries. It is in the middle (meso) between the capillaries (angis). It is contained by the basement membrane, which surrounds both the capillaries and the mesangium.

This term is often used interchangeably with mesangial cell, but in this context refers specifically to the intraglomerular mesangial cells. These cells are phagocytic and secrete the amorphous basement membrane-like material known as the mesangial matrix. They are typically separated from the lumen of the capillaries by endothelial cells.

References

  • Nielsen, S.; Kwon, T.H.; Fenton, R.A.; Praetorious, J. Anatomy of the Kidiney. In: Rector, F. C.; Brenner, B. M. Brenner & Rector's the kidney (em ). 9. ed. Philadelphia: Elsevier Saunders, 2012. 31-93 pp. vol. 1. ISBN 978-1-4160-6193-9.
  • Kriz, W.; Elger, M.; Mundel, P.; Lemley, K.V. (Abril de 1995) "Structure-stabilizing forces in the glomerular tuft"[1]. J Am Soc Nephrol. 5: 1731-1739. PMID 7787139.
  • Schlöndorff, D. (Junho de 1996) "Roles of the mesangium in glomerular function"[2]. Kidney International 49: 1583—1585. DOI:10.1038/ki.1996.229.
  • Phua YL, Chu JY, Marrone AK, Bodnar AJ, Sims-Lucas S, Ho J. "Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival" Physiol Rep. 2015 Oct;3(10). pii: e12537. doi: 10.14814/phy2.12537. PMID 26438731.

External links


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.