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Nim811

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Subject: Mitochondrial permeability transition pore
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Nim811

Template:Chembox ChEMBL
NIM811
Identifiers
CAS number 143205-42-9 YesY
PubChem 6473876
UNII 96262S4I14 YesY
Jmol-3D images Image 1
Properties
Molecular formula C62H111N11O12
Molar mass 1202.61 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

NIM811 is a mitochondrial permeability transition inhibitor. Also known as N-methyl-4-isoleucine cyclosporin, it is a four-substituted cyclosporine analogue that binds to cyclophilin, however this binary complex cannot bind to calcineurin, and therefore lacks immunosuppressive activity.


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