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Prrx2

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Title: Prrx2  
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Subject: PRRX1, Homeobox, Transcription factors, NeuroD, EMX homeogene
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Prrx2

Paired related homeobox 2
Identifiers
Symbols  ; PMX2; PRX2
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Paired mesoderm homeobox protein 2 is a protein that in humans is encoded by the PRRX2 gene.[1][2]

Function

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.[2]

References

  1. ^
  2. ^ a b

Further reading

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