ROS1 (gene)

C-ros oncogene 1 , receptor tyrosine kinase
Available structures
PDB Ortholog search: RCSB
Identifiers
2.7.10.1
RNA expression pattern

Proto-oncogene tyrosine-protein kinase ROS is an enzyme that in humans is encoded by the ROS1 gene.[1][2]

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.[2]

Interactions

ROS1 (gene) has been shown to interact with PTPN6.[3]

References

Further reading



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