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Riedel's thyroiditis

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Title: Riedel's thyroiditis  
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Subject: List of eponymously named diseases, Tamoxifen, Stridor, Thyroiditis, ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseases, Retroperitoneal fibrosis, Acute infectious thyroiditis
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Riedel's thyroiditis

Riedel's thyroiditis
Classification and external resources
ICD-10 9 DiseasesDB eMedicine med/2036

Riedel's thyroiditis, also called Riedel's struma is a chronic form of thyroiditis.

It is believed to be a form of autoimmune thyroiditis.[1]


Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule.[2] This makes the thyroid gland stone-hard and fixed to adjacent structures. The inflammatory process infiltrates muscles and causes symptoms of tracheal compression. Surgical treatment is required to relieve tracheal or esophageal obstruction.

It is now believed that Riedel's thyroiditis is one manifestation of a systemic disease that can affect many organ systems called IgG4-related disease. [3]

Many newly named diseases that begin with the IgG4 immunoglobulin are just new names for single symptoms of the more readily understood name Systemic Antiphospholipid Syndrome, which from the simple word Systemic means that it involves all tissue and organs. We would be better off looking up Systemic Antiphospholipid Syndrome than the individual symptoms related to the Antiphospholipid Antibody (the Immunoglobulin IgG4)


Riedel's thyroiditis is classified as rare. Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid. It is most seen in women.[4]


Therapy usually consists of prednisone(?), nonetheless some cases may require surgery. Tamoxifen has been proposed as part of a treatment plan.[5]

Treatment is directed to surgical relief of compressive symptoms. Tamoxifen may also be beneficial. -Harrison's principle of internal medicine, 17th

The type Surgery which is indicated here is isthmectomy.


It is named for Bernhard Riedel. He first recognized the disease In 1883 and published its description in 1896.[6][7]



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