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Rubidium-82 chloride

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Title: Rubidium-82 chloride  
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Rubidium-82 chloride

Rubidium-82 chloride
Identifiers
CAS number  YesY
PubChem
ChemSpider  YesY
KEGG  YesY
ATC code V09
Jmol-3D images Image 1
Properties
Molecular formula ClRb
Molar mass 117.371 g mol-1
Related compounds
Other cations Caesium chloride

Lithium chloride
Potassium chloride
Rubidium chloride
Sodium chloride

Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)

Rubidium-82 chloride is a form of rubidium chloride using a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 (Bracco Diagnostics) in the use of Myocardial perfusion imaging (imaging of the heart).[1] It is rapidly taken up by heart muscle cells, and therefore can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging.[2] The half-life of the rubidium 82 is only 1.27 minutes; it is normally produced at the place of use by rubidium generators.[3]

References

  1. ^ Th Wackers, Frans J; Bruni, Wendy; Zaret, Barry L (2007-11-19). "Rubidium-82 Generator". Nuclear cardiology: the basics : how to set up and maintain a laboratory.  
  2. ^ Ballinger, James R. (2009). "Integrating Cardiology for Nuclear Medicine Physicians". p. 379.  
  3. ^ K. L. Gould et al. "Clinical feasibility of positron cardiac imaging without a cyclotron using generator-produced rubidium-82." Journal of the American College of Cardiology 1986;7:775-789. [1]

Further reading

  • Clarke, Michael J; Sadler, P. J (1999-06-15). Metallopharmaceuticals: Diagnosis and therapy.  (Note: only about 1/2 page on Rb-generator)
  • Alvarez-Diez, T; Dekemp, R; Beanlands, R; Vincent, J (1999). "Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging in patients using positron emission tomography". Applied Radiation and Isotopes 50 (6): 1015–23.  
  • Waters, S. L.; B. M. Curseys (eds.) (1987). "The Strontium-82/rubidium-82 generator". International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 38 (3): 171–239. 


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