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Title: Sitafloxacin  
Author: World Heritage Encyclopedia
Language: English
Subject: Quinolone, Fluoroquinolone antibiotics, Nucleic acid inhibitors, Gepotidacin, Nitrofuran
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
Clinical data
Legal status
  • (Prescription only)
Routes of
CAS Registry Number  N
ATC code J01
PubChem CID:
ChemSpider  Y
Chemical data
Formula C19H18ClF2N3O3
Molecular mass 409.81

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic[1] that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.


  • See also 1
  • References 2
  • Further reading 3
  • External links 4

See also


  1. ^ Anderson, DL. (Jul 2008). "Sitafloxacin hydrate for bacterial infections.". Drugs Today (Barc) 44 (7): 489–501.  

Further reading

  • Keating GM (April 2011). "Sitafloxacin: in bacterial infections". Drugs 71 (6): 731–44.  

External links

  • (Japanese) Gracevit グレースビット (PDF) Daiichi Sankyo Co. January 2008.
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