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Terminal bronchiole

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Title: Terminal bronchiole  
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Terminal bronchiole

Terminal bronchiole
Diagram of the alveoli with both cross-section and external view.
Latin Bronchiolus terminalis
Gray's subject #240 1098
Code Template:TerminologiaHistologica

A terminal bronchiole is a bronchiole at the end of the conducting zone. At the transition into the respiratory zone, alveoli become present.

The terminal bronchiole is the most distal segment of the conducting zone. It branches off the lesser bronchioles. Each of the terminal bronchioles divides to form respiratory bronchioles which contain a small number of alveoli. Terminal bronchioles are lined with simple cuboidal epithelium containing Clara cells. Terminal bronchioles contain a limited number of ciliated cells and no goblet cells. Clara cells are non-ciliated, rounded protein secreting cells. Their secretions are a nonsticky, proteinaceous compound to maintain the airway in the smallest bronchioles. The secretion, called surfactant, reduces surface tension, allowing for bronchioles to expand during inspiration and keeping the bronchioles from collapsing during expiration. Clara cells, a stem cell of the respiratory system, produce enzymes that detoxify substances dissolved in the respiratory fluid.

External links

  • eMedicine Dictionary
  • Diagram at
  • Histology at

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