EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION : EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION: EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION

By KAYA, Şeyda, Dr.

Book Id: WPLBN0100750938
Format Type: PDF (eBook)
File Size: 14.53 MB.
Reproduction Date: 10/20/2025

Title:	EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION : EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION: EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION
Author:	KAYA, Şeyda, Dr.
Volume:
Language:	English
Subject:	Non Fiction, Science, Gene-based Therapeutics, Gene Therapy, Biopharmaceuticals, Biotechnology, Genomic Medicine, Molecular Therapeutics, Drug Development, Bioprocess Engineering, Cellular Engineering, Genetic Engineering, Biomanufacturing, Recombinant Protein Production, Advanced Therapeutics, Biomedical Innovation, Translational Medicine, Therapeutic Targeting
Collections:	Authors Community, Technology
Historic Publication Date:	2025
Publisher:	BZT TURAN PUBLISHING HOUSE

Member Page:	ANIL CAN
Citation APA MLA Chicago Kaya, D. Ş. (2025). EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION : EMERGING FRONTIERS IN GENE-BASED THERAPEUTICS AND BIOPHARMACEUTICAL PRODUCTION. Retrieved from https://www.self.gutenberg.org/

Description
A chapter on semi-synthetic organisms and expanded genetic alphabets explores new biological systems that expand the boundaries of genetic engineering, while the next chapter explores the functions of synthetic gene circuits in cellular therapeutics. The practical sections of the book explore cell-line engineering approaches for the production of cellbased therapies and the potential of plant systems for biopharmaceutical production. The final chapter presents a systems biology perspective on gene-based biopharmaceutical discovery through the integration of network pharmacology and multi-omics approaches. We believe that this work, by integrating diverse aspects of gene-based therapeutics and biopharmaceutical manufacturing processes, will serve as a valuable resource for researchers, clinicians, and academics. We also hope iv that the book will foster interdisciplinary collaborations and inspire new research ideas in this field.

Summary
Gene-based therapeutics and biopharmaceutical production are among the fastest-growing and most promising areas of modern biotechnology. Advances in genome editing technologies, the integration of cellular engineering strategies and omics-based analyses are leading to revolutionary changes in therapeutic approaches. However, these innovations require a deep understanding of both fundamental biological mechanisms and manufacturing and safety processes. Consequently, the need for up-to-date resources that combine scientific knowledge with a holistic approach is growing. This book is designed to comprehensively cover current developments in gene-based therapeutics and biopharmaceutical manufacturing. The chapters are structured to cover both the fundamental biochemical background and clinical and manufacturing applications. The first section focuses on the biochemical processes involved in the design and production of gene-based biopharmaceuticals. The following section provides a detailed discussion of the fundamental principles, therapeutic applications, and safety aspects of CRISPR technology.

Table of Contents
CHAPTER 1 Biochemical Foundations of Gene-based Biopharmaceutical Design & Production...................................................................................................................1 Mustafa Murat Öztürk CHAPTER 2 CRISPR-Based Gene Therapies: Fundamentals, Applications, and Safety .........................................................................................................................15 Abdul Saltuk Buğra Daş CHAPTER 3 Semi-synthetic Organisms with Expanded Genetic Alphabets ...........43 Dilek Arslan Ateşşahin CHAPTER 4 Synthetic Gene Circuits in the Cellular Therapeutics.............................59 Sevgi Durna Daştan CHAPTER 5 Cell-line Engineering for Cell-based Therapeutics Production ............77 İnanç Baral CHAPTER 6 Plant Molecular Farming for Biopharmaceutical Production................95 Eda Sönmez Gürer viii CHAPTER 7 Integration of Network Pharmacology and Multi-Omics Approaches in Gene-Based Biopharmaceutical Discoveries..............................................111 Şeyda Kaya