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Periarteriolar lymphoid sheaths

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Title: Periarteriolar lymphoid sheaths  
Author: World Heritage Encyclopedia
Language: English
Subject: Trabecular arteries, Trabeculae of spleen, Mantle zone, Trabecular veins, Sentinel lymph node
Publisher: World Heritage Encyclopedia

Periarteriolar lymphoid sheaths

Periarteriolar lymphoid sheaths (or periarterial lymphatic sheaths, or PALS) are a portion of the white pulp of the spleen. They are populated largely by T cells and surround central arteries within the spleen; the PALS T-cells are presented with blood borne antigens via myeloid dendritic cells.

(This is in contrast to the lymphoid portions of the white pulp, where B cells predominate.)

External links

  • Histology image: 07703loa – Histology Learning System at Boston University
  • Histology image: 62_06 at the University of Oklahoma Health Sciences Center
  • Diagram at
  • Diagram
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