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Cacnb1

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Cacnb1

Calcium channel, voltage-dependent, beta 1 subunit
PDB rendering based on 1t0h.
Available structures
PDB Ortholog search: RCSB
Identifiers
CACNB1 Gene
RNA expression pattern

Voltage-dependent L-type calcium channel subunit beta-1 is a protein that in humans is encoded by the CACNB1 gene.[1][2][3]

The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.[3]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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