World Library  
Flag as Inappropriate
Email this Article

Hoxc8

Article Id: WHEBN0014770935
Reproduction Date:

Title: Hoxc8  
Author: World Heritage Encyclopedia
Language: English
Subject: Homeobox, Transcription factors, NeuroD, EMX homeogene, Nur (biology)
Collection: Transcription Factors
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Hoxc8

Homeobox C8
Identifiers
Symbols  ; HOX3; HOX3A
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Homeobox protein Hox-C8 is a



This article incorporates text from the United States National Library of Medicine, which is in the public domain.

External links

  • Acampora D, D'Esposito M, Faiella A, et al. (1990). "The human HOX gene family". Nucleic Acids Res. 17 (24): 10385–402.  
  • Boncinelli E, Acampora D, Pannese M, et al. (1990). "Organization of human class I homeobox genes". Genome 31 (2): 745–56.  
  • Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH (1987). "Cognate homeo-box loci mapped on homologous human and mouse chromosomes". Proc. Natl. Acad. Sci. U.S.A. 83 (23): 9104–8.  
  • Simeone A, Mavilio F, Acampora D, et al. (1987). "Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development". Proc. Natl. Acad. Sci. U.S.A. 84 (14): 4914–8.  
  • Cannizzaro LA, Croce CM, Griffin CA, et al. (1987). "Human homeo box-containing genes located at chromosome regions 2q31----2q37 and 12q12----12q13". Am. J. Hum. Genet. 41 (1): 1–15.  
  • Lawrence HJ, Stage KM, Mathews CH, et al. (1993). "Expression of HOX C homeobox genes in lymphoid cells". Cell Growth Differ. 4 (8): 665–9.  
  • Apiou F, Flagiello D, Cillo C, et al. (1996). "Fine mapping of human HOX gene clusters". Cytogenet. Cell Genet. 73 (1–2): 114–5.  
  • Flagiello D, Gibaud A, Dutrillaux B, et al. (1997). "Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines". FEBS Lett. 415 (3): 263–7.  
  • Shi X, Yang X, Chen D, et al. (1999). "Smad1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling". J. Biol. Chem. 274 (19): 13711–7.  
  • Prévôt D, Voeltzel T, Birot AM, et al. (2000). "The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation". J. Biol. Chem. 275 (1): 147–53.  
  • Bai S, Shi X, Yang X, Cao X (2000). "Smad6 as a transcriptional corepressor". J. Biol. Chem. 275 (12): 8267–70.  
  • Wan M, Shi X, Feng X, Cao X (2001). "Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression". J. Biol. Chem. 276 (13): 10119–25.  
  • Schaefer LK, Wang S, Schaefer TS (2001). "Functional interaction of Jun and homeodomain proteins". J. Biol. Chem. 276 (46): 43074–82.  
  • Waltregny D, Alami Y, Clausse N, et al. (2002). "Overexpression of the homeobox gene HOXC8 in human prostate cancer correlates with loss of tumor differentiation". Prostate 50 (3): 162–9.  
  • Kosaki K, Kosaki R, Suzuki T, et al. (2002). "Complete mutation analysis panel of the 39 human HOX genes". Teratology 65 (2): 50–62.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.  
  • Bayarsaihan D, Enkhmandakh B, Makeyev A, et al. (2003). "Homez, a homeobox leucine zipper gene specific to the vertebrate lineage". Proc. Natl. Acad. Sci. U.S.A. 100 (18): 10358–63.  
  • Luo L, Yang X, Takihara Y, et al. (2004). "The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions". Nature 427 (6976): 749–53.  

Further reading

  1. ^ McAlpine PJ, Shows TB (August 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460.  
  2. ^ Scott MP (December 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3.  
  3. ^ a b "Entrez Gene: HOXC8 homeobox C8". 
  4. ^ Liu Y (Jan 2014). "Microarray-based identification of nerve growthpromoting genes in neurofibromatosis type I.". J Mol Med Rep 9 (1): 192–6.  
  5. ^ Bai, S; Shi X; Yang X; Cao X (March 2000). "Smad6 as a transcriptional corepressor". J. Biol. Chem. (UNITED STATES) 275 (12): 8267–70.  
  6. ^ Shi, X; Yang X; Chen D; Chang Z; Cao X (May 1999). "Smad1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling". J. Biol. Chem. (UNITED STATES) 274 (19): 13711–7.  

References

HOXC8 has been shown to interact with Mothers against decapentaplegic homolog 6[5] and Mothers against decapentaplegic homolog 1.[6]

Interactions

See also

Contents

  • See also 1
  • Interactions 2
  • References 3
  • Further reading 4
  • External links 5

[4] type 1. neurofibromatosis HOXC8 was found to have activity in promoting nerve growth and its expression is dysregulated in patients suffering from [3]

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.