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Kcnj6

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Subject: G protein-gated ion channel, Inward-rectifier potassium ion channel
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Kcnj6

Potassium inwardly-rectifying channel, subfamily J, member 6
Identifiers
KCNJ6 Gene
RNA expression pattern

G protein-activated inward rectifier potassium channel 2 is a protein that in humans is encoded by the KCNJ6 gene.[1][2][3]

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.[3]

Interactions

KCNJ6 has been shown to interact with KCNJ9[4][5] and DLG1.[6]

See also

References

Further reading

External links

  • Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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