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Sox14

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Title: Sox14  
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Subject: Transcription factors, NeuroD, EMX homeogene, Engrailed (gene), HOXC5
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Sox14

SRY (sex determining region Y)-box 14
PDB rendering based on 1gt0.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols  ; SOX28
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Transcription factor SOX-14 is a protein that in humans is encoded by the SOX14 gene.[1][2] This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome.[2]

References

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  2. ^ a b

Further reading


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