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Title: Tentoxin  
Author: World Heritage Encyclopedia
Language: English
Subject: Tetrapeptide, Peptides
Publisher: World Heritage Encyclopedia


Chemical structure of tentoxin
IUPAC names
ChemSpider  YesY
Jmol-3D images Image
Molar mass 414.498 g/mol
Melting point 172 to 175 °C (342 to 347 °F; 445 to 448 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N  (: YesY/N?)

Tentoxin is a natural cyclic tetrapeptide produced by phytopathogenic fungus Alternaria alternata. It selectively induces chlorosis in several germinating seedling plants. Therefore, tentoxin may be used as a potential natural herbicide.

Tentoxin was first isolated from Alternaria alternata (syn. tenuis) and characterized by George Templeton et al. in 1967.[1]

Tentoxin has also been used in recent research to eliminate the polyphenol oxidase (PPO) activity from seedlings of higher plants.[2]


  1. ^ Templeton, G. E., C. 1. Grable, N. D. Fulton, W. L. Meyer. 1967. Tentoxin from Alternaria tenuis: its isolation and characterization. Proceedings of the Mycotoxin Research Seminar, Washington, D. C., June 8–9, 1967. United States Department of Agriculture. pp. 27-29
  2. ^ Duke, S.O. & Vaughn, K.C. 1982. Lack of involvement of polyphenol oxidase in ortho-hydroxylation of phenolic compounds in mung bean seedlings. Physiol. Plant. 54: 381-385.

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